What is SCLERODERMA?

Scleroderma is a rare, chronic autoimmune disease affecting skin and internal organs. It results from the immune system attacking the body, causing inflammation and leading to skin tightening, heart, pulmonary, kidney or blood vessel involvement. It may be systemic, called either limited or diffuse disease depending on how much of the skin is involved. It can sometimes be localized, involving only some areas of the skin. It is more frequently seen in women, typically between the ages of 30 and 50. Raynaud's phenomenon, color changes in the digits with cold exposure, is commonly seen in scleroderma. Depending on internal organ involvement, a patient may experience difficulty swallowing, elevated blood pressure, weight loss, digestive difficulties, shortness of breath or joint pain.

Treatment

Treatment of scleroderma primarily alleviates symptoms. Several medications can improve circulation. Acid reducing medication can relieve heartburn. Mycophenolate can be used to treat patients with scleroderma lung disease along with other circulatory medicines used to treat pulmonary arterial hypertension. IVIG or other immunosuppressants are used to treat muscle inflammation and weakness. Patients who have Raynaud's phenomenon must keep their bodies warm with layers of clothing, gloves, socks and shoes in cold weather. Keeping the skin well moisturized and avoiding activities that could injure the skin are important. Exercise and physical therapy help with joint flexibility.